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Rick Santorum wants a victory in the Illinois primary, but the polls aren't in his favor. Anderson Cooper reports.

Michael Hayden says the Obama administration's tough words on Iran put the intelligence agencies in a bind.

WASHINGTON (AP) -- Amid heightened tensions between their nations, President Barack Obama on Tuesday made a direct appeal to the Iranian people, saying there was "no reason for the United States and Iran to be divided from one another."...

Seven people are injured in an explosion in the basement of a police station in south London.

WASHINGTON (AP) -- The top U.S. commander in Afghanistan says efforts to hand over security to the Afghans and wind down the decade-plus war are on track despite anger over a U.S. soldier's alleged massacre of Afghan civilians and the burning of Qurans....

WASHINGTON (AP) -- The Supreme Court has several options in ruling on President Barack Obama's health care overhaul, from upholding the law to striking it down in its entirety. The court also could avoid deciding the law's constitutionality at all, if it finds the lawsuits challenging the law are premature....

Five members of the University of Southern Mississippi pep band have had their scholarships revoked and have been removed from the band after they yelled a derogatory chant at a Puerto Rican player during an NCAA basketball tournament game last week.

A profile of Illinois, latest battleground in the race for the Republican presidential nomination:...

A brief history of recent big screen flops

TOULOUSE, France (AP) -- Police blanketed southern France on Tuesday, searching for a gunman - possibly a racist, anti-Semitic serial killer - who killed four people at a Jewish school and may have filmed his attack....

WASHINGTON (AP) -- The most powerful prescriptions of a tough House GOP budget plan, like a dramatic restructuring of Medicare and big cuts to domestic programs such as Medicaid, food stamps and transportation appear destined to go back on the shelf almost as soon as the measure is passed this week....

JERUSALEM (AP) -- A new Israeli law bans showing overly thin models from local advertising in an attempt to fight the spread of eating disorders....

JERUSALEM (AP) -- A new Israeli law bans showing overly thin models from local advertising in an attempt to fight the spread of eating disorders....

Cardiff City midfielder Stephen McPhail reveals how tennis star Venus Williams has helped in his battle against illness.

Crowds line the streets as the bodies of six soldiers killed by the same blast in Afghanistan arrive back in the UK.

France mounts a large-scale manhunt over fatal shootings at a Jewish school linked with the killings of soldiers, as schools observe a minute's silence

One hundred new high-salary jobs are being created in Northern Ireland as result of a "significant" investment by an international legal services firm.

BEIJING (AP) -- One of China's highest-profile politicians interfered in an investigation involving a family member before he was fired last week, according to a leaked transcript that has escalated what already was the country's biggest political scandal in years....

A campaign to change the ending of videogame Mass Effect 3 has attracted thousands of supporters, and raised more than $70,000 (£44,000) for charity.

OKLAHOMA CITY (AP) -- Residents and businesses from southeast Texas north through western Missouri braced for flooding Tuesday after a violent band of storms brought heavy rain, hail and at least one tornado, with more of the same forecast for the next several days....